Leticia is located in the Amazon rainforest at the junction of the Amazon, Napo and Putumayo rivers. It is the capital of the Colombian Amazon department of Amazonas and, at the time of the 2011 census, had a population of 111,569.
The city is connected by air and river to Iquitos, Peru, and Manaus, Brazil. It is a popular tourist destination, noted for its natural environment and biodiversity.
Leticia was founded in 1668 as a Spanish Jesuit mission named San Pablo de Borburata. It was relocated in 1695 to its present location on the banks of the Amazon. The city was renamed Leticia in honor of Simón BolÃvar's sister, Luisa Leticia.
The city is home to the Amazonas National University.